The authors looked at four members of the tetracycline antibiotic family/class against four different species of bacteria.
Read More...Strain selective in vitro and in silico structure activity relationship of tetracycline antibiotics
The authors looked at four members of the tetracycline antibiotic family/class against four different species of bacteria.
Read More...The effect of the pandemic on the behavior of junior high school students
Here, seeking to understand how the COVID-19 pandemic affected the social interactions of junior high school students, the authors surveyed students, teachers, and parents. Contrary to their initial hypotheses, the authors found positive correlation between increased virtual contact during social isolation and in-person conflict and disregard for social norms after the pandemic. While the authors identified the limitations of their study, they suggest that further research into the effect of online interactions is becoming increasingly important.
Read More...In silico modeling of emodin’s interactions with serine/threonine kinases and chitosan derivatives
Here, through protein-ligand docking, the authors investigated the effect of the interaction of emodin with serine/threonine kinases, a subclass of kinases that is overexpressed in many cancers, which is implicated in phosphorylation cascades. Through molecular dynamics theyfound that emodin forms favorable interactions with chitosan and chitosan PEG (polyethylene glycol) copolymers, which could aid in loading drugs into nanoparticles (NPs) for targeted delivery to cancerous tissue. Both polymers demonstrated reasonable entrapment efficiencies, which encourages experimental exploration of emodin through targeted drug delivery vehicles and their anticancer activity.
Read More...Using machine learning to understand social media discourse on the co-use of tobacco and cannabis
The authors used developed a machine learning tool for studying social media discourse surrounding use of tobacco and cannabis.
Read More...Does emotion regulation moderate the relationship between self-esteem and social desirability?
The authors investigate the relationship between self-esteem, social desirability, and emotion regulation in children and adolescents.
Read More...Optical anisotropy of crystallized vanillin thin film: the science behind the art
Microscopic beauty is hiding in common kitchen ingredients - even vanillin flavoring can be turned into mesmerizing artwork by crystallizing the vanillin and examining it under a polarizing microscope. Wang and Pang explore this hidden beauty by determining the optimal conditions to grow crystalline vanillin films and by creating computer simulations of chemical interactions between vanillin molecules.
Read More...Determining the Hubble constant through the analysis of Abell clusters
Galaxy clusters offer several advantages for measuring H0 compared to traditional methods, such as Cepheid variables or Type Ia supernovae. Unlike individual stars or supernovae, clusters are less affected by local variations in stellar population or interstellar medium properties, providing a more stable and consistent measure over large cosmological distances. This work proposes using galaxy clusters as an alternative method for determining the H0. It provides an independent perspective on the H0 debate and contribute to ongoing efforts to reconcile the differing values obtained from the other two measurements.
Read More...Implementing machine learning algorithms on criminal databases to develop a criminal activity index
The authors look at using publicly available data and machine learning to see if they can develop a criminal activity index for counties within the state of California.
Read More...Star anise and oregano essential oil: A comparative evaluation of antibacterial effect
The authors looked at the antibacterial effects of oregano and star anise essential oils against E. coli or S. epidermis. They found that oregano oil showed antibacterial activity against both E. coli or S. epidermis, and that star anise oil had a larger zone of inhibition in E. coli than tetracycline, a conventional antibiotic.
Read More...Investigating the impact of electrocardiography biofeedback on POTS symptom management
The authors test electrocardiography biofeedback as a treatment for individuals with Postural Orthostatic Tachycardia Syndrome.
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