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The Effects of Antibiotics on Nutrient Digestion

Murea et al. | Oct 06, 2017

The Effects of Antibiotics on Nutrient Digestion

One disadvantage of antibiotic therapy is the potential for unpleasant gastrointestinal side effects. Here, the authors test whether some common antibiotics directly interfere with the digestion of protein, fat, or sugars. This study provides motivation to more carefully investigate the interactions between antibiotics and gut enzymes in order to inform treatment decisions and improve patient outcomes.

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Effect of pH on the antibacterial properties of turmeric

Ganga et al. | Aug 31, 2023

Effect of pH on the antibacterial properties of turmeric

Some spices have antimicrobial or antibacterial properties that people have already tested. Turmeric has a wide variety of uses and has even been implemented in alternative medicine as a treatment for cancer, inflammation, osteoarthritis, and other diseases. We tested the antimicrobial effects of turmeric under two different pHs to characterize this effect in vitro. Decreasing the pH of a solution of turmeric may increase antibacterial properties.

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Simulating single versus cocktail antibiotic effects on the human gut microbiome

Patel et al. | Jul 19, 2026

Simulating single versus cocktail antibiotic effects on the human gut microbiome
Image credit: Volodymyr Hryshchenko

This study, uses SimulATe to model changes in microbial diversity and community structure upon administering a cocktail of antibiotics versus a single antibiotic. The authors hypothesized that antibiotic cocktails, particularly those combining broad-spectrum drugs like tetracyclines and trimethoprims, would cause a more significant reduction in gut microbial diversity compared to single-drug treatments. The findings confirmed a greater loss of microbial diversity with combinatorial treatments compared to single-drug treatments. While individual antibiotics dynamically reshaped the surviving species of the microbiome, antibiotic cocktails frequently cleared all species of the gut microbiome.

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