Browse Articles

Modeling the heart’s reaction to narrow blood vessels

Athulathmudali et al. | May 22, 2023

Modeling the heart’s reaction to narrow blood vessels

Cardiovascular diseases are the largest cause of death globally, making it a critical area of focus. The circulatory system is required to make the heart function. One component of this system is blood vessels, which is the focus of our study. Our work aims to demonstrate the numeric relationship between a blood vessel's diameter and the number of pumps needed to transport blood.

Read More...

Deciphering correlation and causation in risk factors for heart disease with Mendelian randomization

Singh et al. | Feb 08, 2023

Deciphering correlation and causation in risk factors for heart disease with Mendelian randomization
Image credit: Robina Weermeijer

Here, seeking to identify the risk of coronary artery disease (CAD), a major cause of cardiovascular disease, the authors used Mendelian randomization. With this method they identified several traits such as blood pressure readings, LDL cholesterol and BMI as significant risk factors. While other traits were not found to be significant risk factors.

Read More...

Pressing filtration for extraction of cabbage dietary fiber and soluble components

Xie et al. | Nov 16, 2025

Pressing filtration for extraction of cabbage dietary fiber and soluble components
Image credit: Shelley Pauls

Here the authors introduce pressing filtration as a novel, efficient, and low-energy method for extracting dietary fiber from cabbage, which successfully retains heat-sensitive nutrients and achieves a high fiber yield. The study demonstrates the scalability and economic viability of this technique for commercial use, highlighting that the resulting high-fiber cabbage powder can be incorporated into familiar foods like hamburger buns and beef patties without compromising taste or sensory quality.

Read More...

Quantifying right atrial dilation relative to atrial septal defect size using an experimental model

Lee et al. | Dec 06, 2025

Quantifying right atrial dilation relative to atrial septal defect size using an experimental model
Image credit: jesse orrico

To address the limitations in predicting the severity of Atrial Septal Defect (ASD), here the authors utilized a fluid-filled chamber model to quantify the relationship between defect size and right atrial fluid output. The findings confirmed that larger ASD diameters result in a linear increase in fluid output, validating a cost-effective model that can improve clinical prognosis and treatment planning for heart failure risks.

Read More...

Survival analysis in cardiovascular epidemiology: nexus between heart disease and mortality

Lachwani et al. | Oct 23, 2024

Survival analysis in cardiovascular epidemiology: nexus between heart disease and mortality

In 2021, over 20 million people died from cardiovascular diseases, highlighting the need for a deeper understanding of factors influencing heart failure outcomes. This study examined multiple variables affecting mortality after heart failure, using random forest models to identify time, serum creatinine, and ejection fraction as key predictors. These findings could contribute to personalized medicine, improving survival rates by tailoring treatment strategies for heart failure patients.

Read More...

Study of PINN sensor layout in evaluating WSS with application to patient-specific carotid flow

Nie et al. | Sep 04, 2026

Study of PINN sensor layout in evaluating WSS with application to patient-specific carotid flow

Physics‑Informed Neural Networks (PINNs) offer a promising way to estimate blood‑flow behavior in arteries, especially near the vessel wall where traditional methods struggle. In this study, students tested how sensor density and placement affect PINN accuracy in modeling carotid artery flow and found that accuracy improves up to a moderate sensor density and depends strongly on how close sensors are placed to the arterial wall. Applying the optimized configuration to a patient‑specific carotid model produced velocity predictions closely matching computational fluid dynamics results, highlighting PINNs’ potential for future personalized cardiovascular assessment.

Read More...