This study used single-cell RNA sequencing to examine whether B cells can predict response to pembrolizumab and radiation therapy in patients with triple-negative breast cancer.
Read More...B cell dynamics as predictive markers in triple-negative breast cancer treated with Pembrolizumab & radiation
This study used single-cell RNA sequencing to examine whether B cells can predict response to pembrolizumab and radiation therapy in patients with triple-negative breast cancer.
Read More...Study of PINN sensor layout in evaluating WSS with application to patient-specific carotid flow
Physics‑Informed Neural Networks (PINNs) offer a promising way to estimate blood‑flow behavior in arteries, especially near the vessel wall where traditional methods struggle. In this study, students tested how sensor density and placement affect PINN accuracy in modeling carotid artery flow and found that accuracy improves up to a moderate sensor density and depends strongly on how close sensors are placed to the arterial wall. Applying the optimized configuration to a patient‑specific carotid model produced velocity predictions closely matching computational fluid dynamics results, highlighting PINNs’ potential for future personalized cardiovascular assessment.
Read More...Canopy complexity and plant morphology determine detectability in multi-perspective drone imagery
Multi-perspective drone imagery (adding oblique views to top-down shots) raised crop classification accuracy from 35.73% to 52.93% across five species. The improvement scaled with canopy complexity, from +4.2% for simple rice to +38.1% for structurally complex sugarcane.
Read More...Analyzing the effects of genetic mutations in BRCA1, BRCA2, BARD1, and MLH1 in causing different cancers
This paper utilizes multiple publicly available cancer datasets to explore the abundance of different genetic dependencies across various cancer types. They explore this by looking at four genes highly associated with cancer and their genetic and pathogenic relationships.
Read More...Dantrolene-induced ER stress alters sleep in Drosophila melanogaster
A model for angle evolution in conical piles formed using the fixed funnel method
When granular materials are poured onto a surface, they form conical piles whose slopes increase before reaching a stable angle of repose. We found that this angle evolution follows a previously unrecognized two-phase exponential growth pattern that is conserved across granular materials with diverse particle properties. The parameters of this model correlate with particle friction and are influenced by deposition conditions, providing a quantitative framework for describing pile formation.
Read More...The role of Gymnema sylvestre tea in modulating the perception of sweetness
This study investigates the ability of Gymnema sylvestre tea to acutely suppress sweet taste perception across various food groups. Our findings demonstrate how this natural botanical can reduce sugar cravings, offering a potential complementary strategy for managing dietary intake in type 2 diabetes.
Read More...Algorithmic barriers: Investigating student perceptions of AI bias in subjective “culture fit” hiring
This study investigated perceptions of the emerging workforce toward the use of artificial intelligence in hiring, specifically for assessing subjective "culture fit." Through a mixed-methods survey of 150 high school and early-college students in Nepal, we found a significant disconnect between organizational adoption of AI and the profound skepticism of young job candidates, who express deep concerns about fairness, transparency, and the potential for AI to perpetuate systemic discrimination.
Read More...Impact of contamination variability on convolutional neural network accuracy in recycling classification
The authors looked at the ability of a convolutional neural network (CNN) to sort contaminated recycling, with varying levels of contamination. They found as contamination levels increased, the CNN faced more difficulty correctly classifying items.
Read More...Weather-based power outage prediction in New York City: An ensemble machine learning approach
This study contributes to our understanding of how urban energy systems respond to climate variability and inform strategies for enhancing power grid resilience. The findings can help inform urban planners and infrastructure developers by identifying the factors that make regions within a power grid more vulnerable.
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