Browse Articles

Effects of Prolonged Azithromycin Therapy on Bacterial Resistance to Functionally Analogous Antibiotics

Gibbs et al. | Dec 04, 2020

Effects of Prolonged Azithromycin Therapy on Bacterial Resistance to Functionally Analogous Antibiotics

In this study, the authors investigate a potential case of cross antibiotic-resistance. Using swabs from an individual who received long-term treatments of azithromycin, they addressed the question of whether any bacteria in this individual might develop resistance to not only azithromycin, but also other antibiotics with similar structures. This study cleverly addresses the important issue of antibiotic resistance from a new and thoughtful approach.

Read More...

Drosophila proteins as human surrogates for early drug discovery: Findings from detailed structural analysis

Shankar et al. | Oct 11, 2026

<i>Drosophila</i> proteins as human surrogates for early drug discovery: Findings from detailed structural analysis

This study examines the possibility of utilizing proteins from Drosophila melanogaster in early drug discovery. Structural and sequence analysis of five diverse Drosophila proteins and its human homologs were conducted. Drosophila proteins with high conservation of amino acids at functionally significant positions are better candidates for use as human surrogate in drug discovery efforts.

Read More...

Cathodal Galvanotaxis: The Effect of Voltage on the distribution of Tetrahymena pyriformis

Zheng et al. | Jun 10, 2019

Cathodal Galvanotaxis: The Effect of Voltage on the distribution of <em>Tetrahymena pyriformis</em>

The surface of the unicellular eukaryote, Tetrahymena pyriformis, is covered with thousands of hair-like cilia. These cilia are very similar to cilia of the human olfactory and respiratory tracts making them model organisms for studying cilia function and pathology. The authors of this study investigated the effect of voltage on T. pyriformis galvanotaxis, the movement towards an electrical stimulus. They observed galvanotaxis towards the cathode at voltages over 4V which plateau, indicating opening of voltage gated-ion channels to trigger movement.

Read More...

Testing the Impact of a Geometric Curvature Variable on the Accuracy of Econometric Forecasting Models

Punatar et al. | Jul 26, 2026

Testing the Impact of a Geometric Curvature Variable on the Accuracy of Econometric Forecasting Models

Classical financial forecasting models often fail to capture the complex, nonlinear dynamics of the stock market. This study demonstrates that incorporating a single variable to represent the 'geometric curvature' of a time series dramatically improves the accuracy of standard econometric forecasts. Our findings highlight that geometric properties are a significant predictive factor, opening new avenues for more powerful financial modeling.

Read More...

A 3D printed triboelectric nanogenerator for bridge vibration energy harvesting and sensing

Walavalkar et al. | Jul 19, 2026

A 3D printed triboelectric nanogenerator for bridge vibration energy harvesting and sensing
Image credit: Jakub Żerdzicki

This study strongly illustrates that optimizing 3D printing parameters would enhance a triboelectric nanogenerator's performance. The design improvements substantiate the potential of optimized, 3D-printed TENGs for developing scalable, cost-effective solutions for powering low-energy electronics, particularly in applications such as structural health monitoring.

Read More...