Browse Articles

Here, the authors chose to investigate the efficacy of zinc oxide nanoparticles (ZnO NPs) and cisplatin or zinc ions in inducing cancer apoptosis. While both treatments were found to reduce the proliferation of lung cancer cells, the authors suggest that further studies to identify the mechanism are necessary.

In this study, the authors use high-throughput virtual screening to design and evaluate a set of non-nucleoside reverse transcriptase inhibitors for binding affinity to the protein reverse transcriptase. These studies have important applications toward HIV therapies.

The authors looked at the immunogenicity of a newly developed pneumococcal conjugate vaccine compared to a previously developed one. They found the newly developed vaccine did elicit an immune response.

This study investigates the effects of the PROTAC compound A1874 on CT26 colon carcinoma cells, focusing on its ability to degrade the protein BRD4 and reduce cell viability. While A1874 had previously shown effectiveness in other colon cancer cell lines, its impact on CT26 cells was unknown.

Sadly, around 800,000 people die by suicide worldwide each year. Dong and Pearce analyze health survey data to identify associations between suicidal ideation and relevant variables, such as sleep quality, hopelessness, and anxious behavior.

In this study, the authors investigate the effects of acidity on the survival of commercial probiotic Lovebug bacterial strains.

Kashyap Jha et al. look at the formulation of MAT20, a crude extract of the moringa, amla, and tulsi leaves, as a potential complementary and alternative medicine. Using HeLa cells, they find MAT20 up-regulates expression of inflammation and cell cytotoxicity markers. Their data is important for understanding the anti-cancer and anti-inflammatory properties of MAT20.

The authors looked at the effects of different treatments using flies with neurodevelopmental disorders.

The authors looked at how pharmacokinetics changed depending on the use of an in vitro or an in vivo model.

Here, the authors considered the effects of relationship status and substance use on the mental health of colleges students, where they specifically examined their correlation with depression, anxiety, and the fear of missing out (FoMO). Through a survey of college students they found that those with higher substance misuse had higher levels of anxiety, depression, and FoMO, while those involved in longer-term relationships had lower levels of FoMo and alcohol use.