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Eye color, visual acuity and photophobia: How eye color affects light sensitivity

Spencer et al. | May 20, 2026

Eye color, visual acuity and photophobia: How eye color affects light sensitivity

This study examined whether eye color affects photophobia and vision in elementary school students and staff, finding no significant relationship between eye color, light sensitivity, or visual acuity. However, photophobia was common across age groups, highlighting the need for greater awareness of light sensitivity in learning environments.

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Development of selective RAC1/KLRN inhibitors

Kubrat Neczaj-Hruzewicz et al. | Nov 04, 2024

Development of selective RAC1/KLRN inhibitors

Kalirin is a guanine nucleotide exchange factor (GEF) for the GTPase RAC1, linked to schizophrenia and Alzheimer’s Disease. It plays a crucial role in synaptic plasticity by regulating dendritic spine formation and actin cytoskeleton remodeling, which are essential for creating new synapses. Authors developed two novel compounds targeting kalirin, confirming that predictive modeling can indicate biological activity.

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