Browse Articles

Prediction of molecular energy using Coulomb matrix and Graph Neural Network

Hazra et al. | Feb 01, 2022

Prediction of molecular energy using Coulomb matrix and Graph Neural Network

With molecular energy being an integral element to the study of molecules and molecular interactions, computational methods to determine molecular energy are used for the preservation of time and resources. However, these computational methods have high demand for computer resources, limiting their widespread feasibility. The authors of this study employed machine learning to address this disadvantage, utilizing neural networks trained on different representations of molecules to predict molecular properties without the requirement of computationally-intensive processing. In their findings, the authors determined the Feedforward Neural Network, trained by two separate models, as capable of predicting molecular energy with limited prediction error.

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The Effects of Antioxidants on the Climbing Abilities of Drosophila melanogaster Exposed to Dental Resin

Prashanth et al. | Jan 17, 2019

The Effects of Antioxidants on the Climbing Abilities of <em>Drosophila melanogaster</em> Exposed to Dental Resin

Dental resins can be a source of reactive oxygen species (ROS) which in unruly amounts can be toxic to cellular and overall health. In this report, the authors test whether the consumption of antioxidant rich foods like avocado and asparagus can protect against the effect of dental resin-derived ROS. However, rather than testing humans, they use fruit flies and their climbing abilities as an experimental readout.

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Phytoplankton Plastid Proteomics: Cracking Open Diatoms to Understand Plastid Biochemistry Under Iron Limitation

Nunn et al. | Feb 10, 2017

Phytoplankton Plastid Proteomics: Cracking Open Diatoms to Understand Plastid Biochemistry Under Iron Limitation

In many areas of the world’s oceans, diatoms such as Thalassiosira pseudonana are limited in growth by the availability of iron (Fe), which is an essential nutrient for diatoms. The authors of this study examined if Fe-limitation makes a significant difference in the proteins expressed within the chloroplast, the power source for diatoms, utilizing a new plastid isolation technique specific to diatoms and completing 14 mass spectrometry experiments.

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Stereolithography 3D-printed stents with silica and zirconia nanoparticle reinforcement for intracranial aneurysm treatment

Panda et al. | Oct 12, 2026

Stereolithography 3D-printed stents with silica and zirconia nanoparticle reinforcement for intracranial aneurysm treatment
Image credit: Panda, Jeong, and Srinivasan

This manuscript focuses on improving the mechanical strength and radiopacity of SLA 3D-printed stent materials by incorporating nanoparticles for their application in flow-diverting stents (FDSs) used to treat aneurysms. The authors used biocompatible, bioresorbable resin formulations with varying concentrations of silica and zirconium to enhance tensile strength and radiopacity, respectively. The authors employed SEM to confirm the incorporation of nanoparticles, and CT imaging was used to assess the effect of zirconium-infused FDSs.

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Multi-omic analysis identifies mitochondrial dysfunction as a key feature of hypertrophic cardiomyopathy

Velu et al. | Sep 26, 2026

Multi-omic analysis identifies mitochondrial dysfunction as a key feature of hypertrophic cardiomyopathy

This study used multi-omic analysis to investigate gene expression and DNA methylation patterns associated with hypertrophic cardiomyopathy (HCM). The researchers found significant downregulation of mitochondrial and energy-related pathways, highlighting mitochondrial dysfunction—particularly altered PINK1 expression—as a potential contributor and therapeutic target in HCM.

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