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Cancer is often caused by improper function of a few proteins, and sometimes it takes only a few proteins to malfunction to cause drastic changes in cells. Here the authors look at the genes that were mutated in patients with a type of pancreatic cancer to identify proteins that are important in causing cancer. They also determined which proteins currently lack effective treatment, and suggest that certain proteins (named KRAS, CDKN2A, and RBBP8) are the most important candidates for developing drugs to treat pancreatic cancer.

Climate change is an important and contentious issue that has far-reaching implications for our future. The authors here compare primary temperature and precipitation data from almost 200 years ago against the present day. They find that the average annual temperature in Brooklyn, NY has risen significantly over this time, as has the frequency of precipitation, though not the amount of precipitation. These data stress the need for more ecologically-conscious choices in our daily lives.

Life requires many things, including a hospitable temperature, elements, and energy. Here the authors utilize Newton's laws of physics and information relating a star's luminosity and temperature to determine the minimum and maximum masses and luminosities of planets and stars that would support life as we know it. This work can be used to determine the likelihood of a planet being able to support life based on attributes we can measure from here on Earth.

In this study, we examined the consistency and dependability of Google's Lighthouse tool for measuring website performance, accessibility, SEO, and best practices. Tests conducted on three websites showed that performance scores vary based on the testing mode and website complexity, while other audit categories stay constant. These results provide direction for researchers and developers by highlighting Lighthouse's benefits and drawbacks.

This study examines the possibility of utilizing proteins from Drosophila melanogaster in early drug discovery. Structural and sequence analysis of five diverse Drosophila proteins and its human homologs were conducted. Drosophila proteins with high conservation of amino acids at functionally significant positions are better candidates for use as human surrogate in drug discovery efforts.

The study examined whether high school boys’ water polo teams located near strong programs had similar season performances during the 2024–2025 season.

This study investigated how 18 commonly used cosmetic products affect the growth of two skin-resident bacteria, Staphylococcus epidermidis and Micrococcus luteus. At higher concentrations, half of the tested products inhibited at least one bacterial species, suggesting that some cosmetics may disrupt the skin microbiome and its natural balance.

This paper develops a gelatin-based hydrogel dressing infused with bromothymol blue dye that visibly changes from yellow to blue as wound pH rises from 5.0 to 8.0, signaling possible infection. The color shift was visually detectable and statistically significant across all six Fitzpatrick skin tones, suggesting a low-cost ($0.40/dressing) tool for early infection monitoring in settings with limited access to care.

We observed supernova 2025ngs and created its light curve through aperture photometry. We were then able to determine that 2025ngs was a Type II-P supernova.

Multi-perspective drone imagery (adding oblique views to top-down shots) raised crop classification accuracy from 35.73% to 52.93% across five species. The improvement scaled with canopy complexity, from +4.2% for simple rice to +38.1% for structurally complex sugarcane.